供雷公藤红素(celastrol)!

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雷公藤红素是一种具有多种生物活性的天然产物,来源于中药雷公藤的根皮.现研究表明它具有抗氧化,抗风湿,抗老年痴呆症等功效.同时可以作用于脑神经,肌肉神经,疑难皮肤病.....
具有多种疗效.
Celastrol is a potent anti-inflammatory that is extracted from the root bark of an ivy-like vine in China. Celastrol was used for years as a natural remedy for inflammatory conditions. Several pharmaceutical companies are studying its multiple properties and have found it to be quite intensely immunosuppressive as well as anti-inflammatory. Celastrol inhibits macrophage activation, MHC I and II processing, TNF-alpha, IL1, IL2, and IL6.
Celastrol
"Heat shock protein 70 has been found to arrest neurodegeneration in a fruitfly model. Heat shock proteins got their name because they are produced when cells are stressed by heat or toxins; however, they have a maintenance role in cells as well, helping newly made proteins to fold properly (their chaperone function) and carrying old ones off for degradation.
Celastrol was found to induce heat shock protein 70 as well as 40 and 27 in a variety of cell types, including neurons. It also was found to be cytoprotective, inhibiting apoptosis (cell death) under conditions of severe stress. Because of these exciting results, research with the Bates HD mice will be starting soon. This is clearly a compound to watch."
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